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Test Code CNEI Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation Interpretation, Serum (Non-Orderable)


Specimen Required


Only orderable as part of a profile. For more information see CNES / Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation, Serum.


Useful For

Only orderable as part of a profile. For more information see CNES / Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation, Serum.

 

Interpretation for the Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation

Method Name

Only orderable as part of a profile. For more information see CNES / Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation, Serum.

 

Technical Interpretation

Reporting Name

Comprehensive Neuropathy Interp, S

Specimen Type

Serum

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Clinical Information

This evaluation detects autoantibodies associated with autoimmune and paraneoplastic neuropathies. The panel includes antibodies targeting peripheral nerve, dorsal root ganglia, and nodal/paranodal antigens, improving detection across diverse neuropathy phenotypes.

 

Reflex testing is performed to confirm and further characterize antibody reactivity, enhancing diagnostic sensitivity.

 

Appropriate for patients with subacute or progressive neuropathy, atypical or asymmetric presentations, autonomic involvement, or suspected immune-mediated or paraneoplastic etiologies.

Reference Values

Only orderable as part of a profile. For more information see CNES / Peripheral Nervous System Comprehensive Neuropathy, Autoimmune Evaluation, Serum.

 

An interpretive report will be provided.

Interpretation

The presence of specific autoantibodies and/or combinations of antibodies in this panel provides supportive evidence of an immune-mediated peripheral neuropathy. However, these results must be interpretated in the appropriate clinical context. A negative result does not exclude the possibility of an immune mediated peripheral neuropathy.

Day(s) Performed

Monday through Sunday

Report Available

8 to 12 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

Not Applicable

LOINC Code Information

Result ID Test Result Name Result LOINC Value
621106 Comprehensive Neuropathy Interp, S 69048-7
624190 IFA Notes 48767-8